BALTIMORE—The Orioles had hoped to win a series for the first time since late April on Thursday night against the Toronto Blue Jays.

For a while, it appeared possible.

Anthony Santander’s second RBI single of the night tied the score, 2-2, in fifth.

But in the sixth, the Toronto Blue Jays scored seven runs on their way to a 12-3 win over the Orioles.

Instead of a taut game, the Orioles allowed 10 runs or more for the 11^th time this season. In games decided by five runs or more, the Orioles are 3-18.

“That was a good game through five,” Orioles manager Brandon Hyde said.

After starter Gabriel Ynoa allowed the first of two home runs to Cavan Biggio to lead off the sixth, he was removed. The normally steady Paul Fry allowed five runs for the first time in his career. Evan Phillips allowed two more.

“Ynoa was throwing the ball pretty well, just left a 3-2 sinker kind of in the middle part of the plate,” Hyde said. “It’s 3-2 and set up for Paul Fry right there, and he had a tough time locating and some walks, and next thing you know it got away from us.”

The seven runs scored were the most the Orioles gave up in an inning this season. They allowed 17 hits, two short of their season high.

Josh Lucas allowed three runs in the seventh, including Biggio’s second home run.

Santander had three hits. Chance Sisco hit his second home run.

Marcus Stroman went six innings for Toronto for the win.

The Orioles still have not won a series since April 22-24. In the 14 series since then, they’ve lost 13—11 in succession—and split one.

Ynoa’s night: Ynoa allowed three runs in five-plus innings. He allowed home runs to Biggio in the second and Lourdes Gurriel in the sixth. He left after Gurriel’s homer.

In between, Toronto scored a run on three singles in the third. Gurriel’s single scored Danny Jansen.

“It’s not what I was expecting,” Ynoa said through a translator. “I tried to go longer, to pitch better. I think I left the game pretty close.”

Cashner to wait: Andrew Cashner, who left his last start on June 8 after six innings because of a blister, has been scratched from Friday’s start.

Hyde won’t decide on a starter until Friday, but didn’t think Cashner would have to go on the 10-day injured list.

“I don’t think so,” Hyde said. “I think it’s just going to be a few days. I don’t think it’s going to be long.

“We were hoping it was going to get better. It just didn’t feel right today so we made a kind of last-second decision today to push him back a few days. We need a starter for tomorrow, which was possibly going to be a bullpen day but the way the game turned out tonight it’s not a possibility.”

Norfolk’s starter for Friday is scheduled to be Luis Ortiz, who’s on the 40-man roster. If Cashner’s not put on the IL, the Orioles will have to make a move to add Ortiz or someone else. Hyde indicated that a move would be necessary.

Davis goes the other way: Chris Davis, who unveiled a new batting stance on Wednesday night by lowering his hands, began the fifth inning with a single that rolled into left field.

“It felt so good,” Davis said. “Obviously I’m making some adjustments and trying to do it on the fly and apply it in-game, which is, as you can tell, quite tough. But, yeah, it felt good to get on base and kind of get a rally started and make Stroman work a little. Obviously, he was tough tonight, but it was nice to be part of the action for once.”

Davis is batting .167 after moving his average to .193 on May 10. He spent 10 days on the IL with inflammation in his left hip.

“Health-wise, I felt pretty good,” Davis said. “I felt like I’m as close to 100 percent as you can be right now. And like I said, I’m trying to make adjustments right now. I understand that I haven’t produced even close to where I’m capable of and at some point you just get tired of going out and doing the same thing over and over and expecting a different result.

“So we pretty much scraped everything and started back at square one, and that’s where I’m headed now. It’s encouraging every day to have something to look forward to, to work toward that’s different, so I’m trying to keep my focus on that.”

Big award for Rutschman:  Adley Rutschman, the top overall pick by the Orioles in last week’s draft, won the Golden Spikes award as the top amateur player in the country.

Ben McDonald, who was the last top pick in the draft by the Orioles, also won the award in 1989.