Orioles rightfielder Anthony Santander had to be helped from the field after injuring his left ankle in the first inning against the Miami Marlins Tuesday night.

Santander rolled his ankle trying to get back to first base on a pickoff attempt by Marlins starter Nick Neidert. Santander fell to the ground and later had to supported by manager Brandon Hyde and athletic trainer Brian Ebel.

Austin Hays, who rejoined the club after coming off the injured list before the game, replaced Santander in right field. He made an outstanding leaping catch at the wall in the bottom of the inning.

The Orioles said Santander sprained the ankle and his status is uncertain.

If Santander goes on the injured list, the Orioles could bring back outfielder Ryan McKenna, who was optioned to the alternate training site at Bowie to make room for Hays earlier in the day.